HapCluster++ 2.1.0 (Default branch) |
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HapCluster++ is a software package for linkage
disequilibrium mapping using coalescent theory. It
is based on a Bayesian Markov-chain Monte Carlo
(MCMC) method for fine-scale
linkage-disequilibrium gene mapping using
high-density marker maps. HapCluster++ is a C++
implementation of the method described in the
paper "Fine Mapping of Disease Genes via Haplotype
Clustering" by E.R.B. Waldron, J.C. Whitaker, and
D.J. Balding. Genetic Epidemiology. 30:
170–179. (2006).
License: GNU General Public License (GPL)
Changes:
In this version, it is possible to obtain a Bayes'
factor for each marker locus by running the MCMC
with a fixed disease locus positioned at each
marker.
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